We employed univariate cox proportional hazard regression analysis to identify six prognostic related genes (BAALC, HGF, CPXM1, CCL4, ZBTB10, and B3GNT2) from the GDC TARGET ALL dataset, and constructed a risk score model by establishing the prognostic features of these genes. Here, B3GNT2 is linked to acute lymphoblastic leukemia.