14 studies (Ito et al., 2015; Mitsuhashi et al., 2015; Mima et al., 2016; Sun et al., 2016; Park et al., 2017; Yamaoka et al., 2018; Chen et al., 2019; Kunzmann et al., 2019; Zhang et al., 2019; Boehm et al., 2020; Haruki et al., 2020; Lee et al., 2021; Nie et al., 2021; Yamamoto et al., 2021) reported the correlation between TNM and Fn levels in CRC tissues. Here, FN1 is linked to colorectal carcinoma.