Fecal occult blood testing (FOBT) and carcinoembryonic antigen (CEA), currently the standard noninvasive screening tests (Levin et al., 2008; Zavoral et al., 2009), have limited sensitivity and specificity for CRC (Krzystek-Korpacka et al., 2013). The gene discussed is CEACAM5; the disease is colorectal carcinoma.