In addition, blood eosinophil leukocyte chemotactic factor, IFN-γ, IL-15, IL-6, interferon gamma-induced protein-10, and tumor necrosis factor-α were significantly elevated before disease deterioration in a non-fatal encephalitis SFTS patient, which may be due to encephalitis development (Cui et al., 2015). Here, TNF is linked to encephalitis.