High levels of SFTSV RNA, interferon gamma-induced protein-10, IFN-γ, IL-8, and MCP-1 were detected in the serum from a SFTS patient with hemophagocytic syndrome and neurological damage before death (at 8–12 days of during the course of disease) (Kaneko et al., 2018). This evidence concerns the gene IFNG and hemophagocytic syndrome.