High levels of SFTSV RNA, interferon gamma-induced protein-10, IFN-γ, IL-8, and MCP-1 were detected in the serum from a SFTS patient with hemophagocytic syndrome and neurological damage before death (at 8–12 days of during the course of disease) (Kaneko et al., 2018). Here, CXCL8 is linked to hemophagocytic syndrome.