Additionally, p53 can facilitate dipeptidyl-peptidase 4’s (DPP4) nuclear translocation and join forces with it to form the DPP4-p53 complex, which lowers DPP4-dependent lipid peroxidation and inhibits ferroptosis in colorectal cancer cells (Xie et al., 2017). The gene discussed is TP53; the disease is colorectal cancer.