The Kaplan–Meier survival analysis showed that in cervical cancer patients, the OS, DSS, DFI, and PFI of patients with high expression of PDIA3 were significantly lower than those of patients with low expression, and the patients with low expression of PDIA3 had a long survival time, indicating that high expression of PDI3 was related to poor prognosis, which was consistent with the results of this study. Here, PDIA3 is linked to cervical carcinoma.