IL27 and atherosclerosis: The mice treated with the anti-IL-27p28 antibody in the early stage of atherosclerosis exhibited a 35.4% increase in aortic sinus atherosclerotic lesion size than those treated with PBS (mean aortic sinus plaque area 415.3 ± 40 × 103 μm2 vs 562.2 ± 28 × 103 μm2, respectively; P = 0.013; Figure 1).