In the groups modeling the progression of atherosclerosis (Figure 7(b)), TGF-β (2.80 ± 0.50 − fold vs 1.00 ± 0.08 − fold, respectively; P = 0.005), Foxp3 (2.23 ± 0.43 − fold vs 1.00 ± 0.06 − fold, respectively; P = 0.007), and IL-10 (2.56 ± 0.57 − fold vs 1.00 ± 0.10 − fold, respectively; P = 0.007) showed higher levels in the mice treated with IL-27 than in those treated with PBS. The gene discussed is IL10; the disease is atherosclerosis.