Functionality and cytotoxicity of the αCEA TCE were quantified using in vitro co-culture models with human CRC cell lines that express CEA, including HT-29 (Figure 1C) and COLO 205 (Figure 1D), and human PBMCs (Effector : Target Cell = 5:1). The gene discussed is CEACAM5; the disease is colorectal carcinoma.