More specifically, we have detected increased levels of sICAM-1, CXCL10, CXCL1, CCL5, TIMP-1 and TNFα in tumours treated with VV-αCEA TCE, compared to tumours treated with VV-CTRL or PBS (Figure 5D, Supplementary Figures 11B–H). This evidence concerns the gene TIMP1 and neoplasm.