In contrast, the levels of macrophages M2, T cells, mast cells resting, dendritic cells activated, CD4 memory resting T cells, eosinophils, macrophages M1, gamma delta T cells, CD8 NK cells, naïve B cells and follicular helper T cells were significantly higher than ARHGAP4 in AD patients (Figure 5A). Here, CD8A is linked to Alzheimer disease.