In P2Y12 KO CLP mice, sepsis-induced platelet-leukocyte aggregates values were lower than the WT CLP (Figure 3C; P<0.05, male CLP vs male P2Y12 KO CLP) while no difference between WT CLP and P2Y12 KO CLP was noted in female mice (Figure 3D). This evidence concerns the gene P2RY12 and Sepsis.