P2RY1 and Sepsis: However, the sepsis-induced leukocyte count (white blood cells, lymphocytes, and neutrophils) was not increased in the CLP P2Y12 KO male mice compared to WT CLP male mice (Figures 1A, C, EP<0.05; male CLP vs male P2Y12 KO CLP) but no change in CLP P2Y1 KO male mice was noted (Figures 1A, C, E).