On the other hand, in female mice, the sepsis-induced increase in IL-1β plasma levels was noted while mice were exposed to MRS2279 (Figure 7F, P<0.05; CLP vs CLP MRS2279), while an increase in IL-17 was noted in septic female mice exposed to ticagrelor as compared with septic untreated female mice (Figure 7H, P<0.05; CLP vs CLP MRS2279 and CLP vs CLP + ticagrelor). The gene discussed is IL1B; the disease is Sepsis.