Table 1 shows the differences between the TCGA and CGGA cohorts. GSRS-based risk scores were obtained and were significantly correlated with WHO glioma grade, IDH mutational status, and 1p19q co-deletion status in the datasets (Figures 4A, B). In particular, LGG samples with higher WHO grade, IDH wild type, or 1p19q non-co-deletion showed higher risk scores than the other samples; differences were also seen among the LGG and other samples for histology (Figures 4C, –J). This evidence concerns the gene IDH1 and central nervous system cancer.