The other four included a 69 year old female with CLL and a history of COVID-19 in December, 2020, a 71 year old male with cirrhosis, a 79 year old female with CLL on BTK inhibitor and prior anti-CD20 antibody x years before and a 64 year old male with mild renal insufficiency and anemia. This evidence concerns the gene BTK and anemia (phenotype).