In mice with Osgin1 knockdown, no difference was observed in the serum amylase and lipase levels as well as tissue edema and necrosis between the vehicle and GW4064 group (Figures 5(c)–5(e)), suggesting that the therapeutic effects of GW4064 on pancreatitis were mediated by the promotion of Osgin1 expression. Here, OSGIN1 is linked to pancreatitis.