GNAQ and melanocytic neoplasm: The presence of a nevus of Ota is one of the few predictors of risk for UM and Van Raamsdonk et al. (2009) have identified an 83 and 46% incidence of GNAQ p.Q209L mutations in blue nevi and UM, respectively, underscoring the overlapping relationship GNAQ plays in melanocytic neoplasms and UM.