TP53 and colorectal carcinoma: To explore the relationship between epithelial state and PKCγ expression, DLD-1 and SW480 cells (used mainly because both these cell lines have mutations in both KRAS and TP53, which are frequently observed in CRC, and they retain epithelial traits) were stably overexpressed with SNAI1, an EMT-inducible transcription factor associated with CRC.15