AXL and infection: AXL has been reported to be a receptor for ZIKV entry and infection, and silencing AXL in A549 cells has been shown to reduce ZIKV infection in vitro19,20,21 We first performed co-IP of AXL with an antibody specific against ZIKV E protein and found that indeed AXL could be co-purified with ZIKV E protein (Figure S2H), supporting that AXL is in the proximity of ZIKV E protein during the ZIKV entry.