In patients with a diabetes duration of 5–10 years, plasma levels of sCD163 were correlated to sST2 (rs=0.28, CI95: 0.05–0.48; p = 0.016) and Gal-3 (rs=0.25, CI95: 0.01–0.45; p = 0.038). This evidence concerns the gene LGALS3 and diabetes mellitus.