MYH9 and macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss: This familial case study was aimed at the elucidating qualitative functional and structural alterations of platelets in a hereditary MYH9-related disorder known as the May-Hegglin anomaly or the Sebastian syndrome and characterized by macrothrombocytopenia associated with a tendency for bleeding.