SNAI1 and glioblastoma: In particular, transcription factors zinc-finger E-box-binding (ZEB), the Snail family of zinc-finger transcription factors (SNAIL), SLUG (also a zinc-finger transcription factor), lymphoid enhancer factor (LEF), and the TWIST family have been proved to be related to EMT in GBM cell invasion via the repression of epithelial marker genes and activation of mesenchymal marker genes mediated by various signaling pathways.