In the fully adjusted model, the risk allele in PNPLA3 rs738409 and older age and male sex were identified to be contributing factors for developing hepatic fibrosis (HR, 1.17; 95% CI, 1.04–1.32; HR, 1.07; 95% CI, 1.06–1.08; and HR, 1.36; 95% CI, 1.14–1.63, respectively; Model 3 in Table 4). The gene discussed is PNPLA3; the disease is Hepatic fibrosis.