IFITM3 and COVID-19: After adjusting for SARS-CoV-2 variants and IFITM3 rs6598045 genotypes, COVID-19 mortality was associated with IFITM3 rs6598045 GG (OR 35.16, 95% CI 8.49–145.54) and AG (OR 2.20, 95% CI 1.59–3.05) in Delta variant and with IFITM3 rs6598045 AG (OR 4.10, 95% CI 2.58–6.53) in Alpha variant (Table 3).