IGFBP7 and acute respiratory distress syndrome: The association between proteomic analysis and outcome has recently been investigated by Dong et al. [154] who observed that plasma insulin-like growth factor binding protein 7 (IGFBP7) increased ARDS 28-day mortality (odds ratio [OR], 1.11; 95% confidence interval [CI], 1.04–1.19; p = 0.002) and that the association between IGFBP7 and ARDS 28-day mortality seems to be mediated by the platelet count (OR, 1.03; 95% CI, 1.02–1.04; p = 0.01).