Intravenous administration of Gal-3 in FeCl3-induced thrombosis model accelerated initial thrombus event and increased thrombus area in WT mice but failed to make difference in Dectin-1−/− deficient mice or thrombocytopenic WT mice transfused with Dectin-1−/− platelets [129]. The gene discussed is CLEC7A; the disease is deep vein thrombosis.