SFXN4 and ovarian adenocarcinoma: With the exception of OVCAR8, SFXN4 was up-regulated in all ovarian cancer cell lines examined, including cell lines representative of HGSOC (COV362, OVCAR3 and OVCAR4); endometrioid (MDAH2774 and TOV112D) and ovarian adenocarcinoma (SKOV3) (Fig. 1B).