As shown in Fig. 4A and Supplemental Fig. S2, SFXN4 knockdown decreased levels of all these Fe-S-containing proteins in HGSOC ovarian cancer cell lines (COV362, OVCAR3), ovarian cancer stem cells (FTT), and endometrioid cancer cells (MDAH2774), with the reduction ranging from 30 to 90%, as assessed by western blotting. This evidence concerns the gene SFXN4 and ovarian carcinoma.