Finally, analysis of the public databases [24, 27] confirmed that BCL2, KIT, and MYC, were upregulated in both tuft cell-like SCLC and LCNEC (Fig. 3E), and that tuft cell-like compared to non-tuft cell-like SQCCs expressed higher levels of BCL2 and KIT (P < 0.05), while expression levels of MYC were not statistically different (P = 0.09) (Fig. S8A). Here, BCL2 is linked to large cell neuroendocrine carcinoma.