EPHA2 and cancer: EPHA2 is one of the most prominent EPH receptor family members in cancer, as its overexpression has been linked to treatment resistance, metastatic potential and disease progression in several cancer entities and has been shown to affect both cell proliferation and cell migration (Martini et al. 2019; Xiao et al. 2020; Miao et al. 2009; Zhuang et al. 2010; Koch et al. 2015).