Three genes including FLCN, MOB3A and TRPM7 were significantly increased (Figure 6C–E), while the remaining six genes including ATR, DDB1, SOCS3, PTPN1, OGDH and EID2 were significantly decreased (Figure 6F–K) in AD samples compared with normal ones. The gene discussed is PTPN1; the disease is Alzheimer disease.