CASP3 (Caspase 3) is a group of proteases that play a key executive role during apoptosis, capable of eliminating redundant and nonfunctional synapses and removing extra cells during early childhood development, and play an important role in embryonic neuronal development.[43] Experiments have shown that Casp3-deficient mice exhibit abnormal motor behaviors such as impaired social interaction, limited interest, and repetitive stereotypes associated with endoplasmic reticulum stress. Here, CASP3 is linked to Endoplasmic Reticulum Stress.