The CFAP47 gene has recently been linked to rare cases of asthenoazoospermia and male infertility.[16] When the secondary structure of the CFAP47 protein was evaluated using Interpro, amino acids 132-1303 were predicted to comprise an immunoglobulin-like (Ig-like) folding domain, while amino acids 1746 to 1869 were predicted to comprise a calponin homology domain. This evidence concerns the gene CFAP47 and male infertility.