GPT and primary biliary cholangitis: However, only four patients with an IgG level of more than 2 ULN and ALT level of more than 5 ULN satisfied OS criteria according to Paris Standard.[23] The International Autoimmune Hepatitis Group recommends the use of variant syndrome to describe patients with two disease characteristics.[24] If PBC patients have abnormal examination results, such as elevated IgG and transaminases, variant syndrome should be suspected.[25] Compared with the increase in transaminases, the increase in IgG level may be more specific, so the IgG index was selected for analysis.