Alb is known to be a prognostic factor for elderly people.[20] Patients with malnutrition, low Alb level, could be a risk factor for mortality due to infectious diseases.[28] Our previous study also suggests that Alb could be a risk factor for the development of aspiration pneumonia in elderly patients with femoral neck and trochanteric fractures.[29] These studies suggest that dual measurement procedure can improve prognostic accuracy rather than single CURB-65 measurement. The gene discussed is ALB; the disease is nutritional deficiency disease.