BRCA1 and breast carcinoma: In order to differentiate between BRCA1/2 germline or somatic mutations, same analyses were performed concerning the distribution of the HRD score and S3 proportion according to BRCA 1/2 mutational status (germline or somatic) considering the whole cohort (n = 928) (Additional file 3: supplemental figure 2E–F (S2 E–F)) or by breast cancer subtypes (standard pathological classification or PAM50 subtypes) (Additional file 3: supplemental figure 2A–D (S2 A–D)).