For FOXM1 protein expression, although there was no significant difference in its expression between tumor tissue and normal samples (both P > 0.05, with one-way ANOVA, respectively, Fig. 3 C-D); both the percentage of positive cells and the average fluorescence intensity of FOXM1 was increased in cancer tissues than in GIN tissue samples (P < 0.001 and P = 0.002, with one-way ANOVA, Fig. 3 C-D). The gene discussed is FOXM1; the disease is neoplasm.