With respect to comparisons between high CNS disease activity group and the moderate activity group, there were increased frequencies of lung involvement (0% vs. 12%, p < 0.05), high-titer (1:1000) ANA (11.1% vs. 36.4%, p < 0.05), and immune thrombocytopenia (218.11 ± 68.47 versus 137.94 ± 84.67, p < 0.05). This evidence concerns the gene BTG3 and autoimmune thrombocytopenic purpura.