Consistent with increased circulating lipids and fatty acids in obesity, a 6-month WD induced increased expression of fatty acid and lipid transporters Cd36, Fabp4, Fabp5 and Abca1 in liver ECs, which was partially restored by the reversion diet (Fig. 5i). The gene discussed is FABP4; the disease is obesity due to melanocortin 4 receptor deficiency.