Last, thelevels of inflammatory cytokines, including IL-1β, IL-6 andTNF-α, as well as adhesion molecules, including VCAM-1, ICAM-1 andE-selectin in both plasma (Supplementary Table 2) and MAECs (Fig. 1f) of KO mice were significantly higher than those in WT mice,which were more severe in WD mice when compared to NCD mice. The gene discussed is VCAM1; the disease is Wilson disease.