NRG4 and atherosclerosis: Here we showthat BAT-derived neuregulin-4 (Nrg4) ameliorates atherosclerosis in mice.BAT-specific Nrg4 deficiency accelerates vascular inflammation and adhesionresponses, endothelial dysfunction and apoptosis and atherosclerosis in male mice.BAT-specific Nrg4 restoration alleviates vascular inflammation and adhesionresponses, attenuates leukocyte homing and reduces endothelial injury andatherosclerosis in male mice.