Within pediatric data sets, a comparison of cancer samples and normal tissue from the NCI OncoGenomics database (Supplementary Fig. S2C) also demonstrates higher MRC2 expression in the majority of sarcoma samples compared with the mean normal tissue expression (Supplementary Fig. S2c), with notable elevation of MRC2 expression in osteosarcomas. The gene discussed is MRC2; the disease is osteosarcoma.