Notably, in the group with the most noticeable anti-PD1 delivery (high H3 group; Fig. 4E), we observed a fivefold increase in the tumor area covered by CD64+ cells (Fig. 4F) and a fivefold increase in the colocalization between CD64 and anti-PD1, as compared to control (Fig. 4G). This evidence concerns the gene FCGR1A and neoplasm.