CD4 and neoplasm: We did not find any inflammatory differences among treatment groups in tumor tissue based on the number of CD4+ or CD8+ T cells, B cells, neutrophils, dendritic cells, and myeloid cells; however, our analysis showed an abundance of PD1+ CD8 T cells within the TME that was not observed in the contralateral nontumor hemisphere that was sonicated with the same exposure conditions (high H3) (Fig. 4H).