HSPs inhabit nearly all subcellular compartments and our group was among the first who demonstrated a tumor cell–specific surface expression of Hsp70 on a large variety of malignant cell types of human and murine origin (Multhoff et al. 1995; Hantschel et al. 2000; Stangl et al. 2011a, b). The gene discussed is HSPA1A; the disease is neoplasm.