APOC1 and Alzheimer disease: Given associations of the ε4 alleles with Aβ42 and tau, we examined associations of the AD-risk differentiating compound genotypes comprising the ε4-encoding rs429358, TOMM40 rs2075650, and APOC1 rs12721046 SNPs with Aβ42 and tau measured at baseline (see Table 3 and Supplementary Table 5 for notations and the results).