Our study showed that AVP inversely correlated with presence of CAD which is similar to studies done by Gunes et al,4 Vasudeva chetty et al,7 Sen et al15 and Marakkagari Vamsikrishna et al16 Our study reported < 78 cm/s as cut-off value of the AVP for predicting CAD with sensitivity of 86.4% and specificity of 84.6% (P ≤ 0.0001, AUC = 0.948). The gene discussed is AVP; the disease is coronary artery disorder.