POLR3A and Intellectual disability: Hiraide et al also reported two sets of compound heterozygous variants in POLR3A, c.1771‐6C > G and c.791C > T, p. (Pro264Leu) and c.1771‐6C > G and c.2671C > T, p. (Arg891*), leading to neuropsychiatric regression and severe intellectual disability in three patients from two families.