Additionally, Kaplan–Meier survival curve analyses showed that overall survival was remarkably better in the CTLA4 low expression group than in the CTLA4 high expression group in ccRCC patients (Figure 2C, Figure S1), indicating that CTLA4 expression was associated with poor prognosis in ccRCC. This evidence concerns the gene CTLA4 and nonpapillary renal cell carcinoma.