TNF and abscess: Complete ECF closure = complete closure of all fistulae at physical examination and complete cessation of the drainage from the fistula without occurrence of any abscess or need for surgery within the first 3 mo following anti-TNF therapyClinical response = reduction in the number of draining fistulae by at least 50% from baselineMaintenance of ECF closure at the end of follow-upOccurrence of abscessesNeed for surgery