After anti-TNF therapy, an abdominal abscess developed in 31% (15/48) patientsAt the end of follow-up, 7%† (3/48) patients developed abdominal abscess3.8%* (1/26) of the 26 patients who needed surgery after anti-TNF therapy developed sepsis. The patient died after surgery from abdominal sepsis. The gene discussed is TNF; the disease is abdominal abscess.