Therefore, it is considered an insulin sensitizer that appears to be associated with its beneficial effects on tyrosine kinase activity and insulin receptor expression.[26] Studies have demonstrated that compared with healthy people, patients with diabetes are at a higher risk of developing cancer, partly because of increased circulating levels of growth factors such as insulin or insulin growth factor 1 and 2 (IGF-1 and 2).[27]. The gene discussed is INS; the disease is diabetes mellitus.