HAT1 and neoplasm: Histone acetyltransferase 1(HAT1) is a type B histone acetyltransferase that regulates the acetylation of histones and non-histones.[35] Existing studies have shown that HAT1 regulates the level of lysine succinylation in a variety of proteins, participates in many cellular physiological and pathological pathways, and increases significantly in multiple tumor tissues.