IGF1 and hereditary endocrine growth disease: The expression of proteins related to hair growth factors, such as insulin-like growth factor-1 and vascular endothelial growth factor, promoted hair growth during hair loss.[52] Regarding physical growth, 2 studies reported on the promotion of growth by increasing the total number of red blood cells and packed cell volume in growth disorders owing to nutrient deficiency.[53,54] By contrast, another study confirmed that increasing insulin-like growth factor-1 and thyroid-stimulating hormone exerted a significant growth effect.[55]