Nucleotide-binding oligomerization domain-like receptor family caspase recruitment domain containing 5 (NLRC5) cg07839457 and branched chain amino acid transaminase 1 (BCAT1) cg20399616 were significantly associated with BMI, obesity and WC [46]. The gene discussed is BCAT1; the disease is obesity due to melanocortin 4 receptor deficiency.