LCN2 and type 2 diabetes mellitus: 131.9 ug/L and 32.35 mg/dl were determined as the best cut-off points of NGAL and sdlDL-C to predict the risk of MACCE of T2DM patients aged ≥ 65 years, with sensitivity of 74.01% and 69.49% and specificity of 78.86% and 73.38%, respectively.