CCDC6 and central nervous system neoplasm: Several of the fusions detected that, to our knowledge, have not been previously reported in CNS tumors included PDGFRA-SCAF11 as well as 2 RET fusions, RET-CCDC6 and RET-PCM1, all of which occurred in cases of IDH-wildtype infiltrating astrocytoma (Fig. 4a, b).